Cellular and Developmental Strategies Aimed at Kidney Tissue Engineering
نویسندگان
چکیده
منابع مشابه
Cellular and developmental strategies aimed at kidney tissue engineering.
BACKGROUND With the rate of kidney disease on the rise, and a serious imbalance between the number of patients requiring a kidney transplant and the number of available donor kidneys, it is becoming increasingly important to develop alternative strategies to restore organ function to diminish the need for human donors. SUMMARY We review the current progress and future directions of a subset o...
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Recent advances in our understanding of the developmental biology of the kidney, as well as the establishment of novel in vitro model systems, have potential implications for kidney tissue engineering. These advances include delineation of the roles of a number of growth factors in the developmental programs of branching morphogenesis and mesenchymal differentiation, a new understanding of the ...
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Vascularisation is considered to be one of the greatest challenges in tissue engineering. Different strategies exist but cell-based approaches have emerged as a promising therapy to achieve successful vascularisation. The use of endothelial cells to engineer vascularised tissues has been extensively investigated. This field of research has evolved with the discovery of endothelial progenitor ce...
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ژورنال
عنوان ژورنال: Nephron Experimental Nephrology
سال: 2014
ISSN: 1660-2129
DOI: 10.1159/000360680